Prevalence, Distribution, and Antifungal Susceptibility Profiles of Candida parapsilosis , C. orthopsilosis , and C. metapsilosis in a Tertiary Care Hospital

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Epidemiology and antifungal susceptibility of Candida species in a tertiary care hospital, Kolkata, India

Background and Purpose: The incidence of fungal infection as well as candidemia has increased significantly, contributing to morbidity and mortality in the developed countries. The alarming increase in infections with multidrug resistant bacteria is due to overuse of a broad spectrum antimicrobials, which leads to over growth of Candida spp.; thus, enhancing its opportunity to cause the disease...

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In vitro fungicidal activities of echinocandins against Candida metapsilosis, C. orthopsilosis, and C. parapsilosis evaluated by time-kill studies.

Anidulafungin, micafungin, and caspofungin in vitro activities against Candida metapsilosis, C. orthopsilosis, and C. parapsilosis were evaluated by MICs and time-kill methods. All echinocandins showed lower MICs (mean MICs, 0.05 to 0.71 mg/liter) and the highest killing rates (-0.06 to -0.05 CFU/ml/h) for C. metapsilosis and C. orthopsilosis rather than for C. parapsilosis (mean MICs, 0.59 to ...

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Geographic distribution and antifungal susceptibility of the newly described species Candida orthopsilosis and Candida metapsilosis in comparison to the closely related species Candida parapsilosis.

Candida orthopsilosis and Candida metapsilosis are recently described species, having previously been grouped with the more prevalent species Candida parapsilosis. Current literature contains very little data pertaining to the distributions and antifungal susceptibilities of these Candida species. We determined the species and antifungal susceptibilities of 1,929 invasive clinical isolates from...

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Distribution, virulence attributes and antifungal susceptibility patterns of Candida parapsilosis complex strains isolated from clinical samples.

It was recently proposed that Candida parapsilosis represents a complex composed of three closely related species, i.e., C. parapsilosis sensu stricto, C. orthopsilosis, and C. metapsilosis. The aim of this study was to describe the distribution of C. parapsilosis complex isolates among clinical samples. We also evaluated antifungal susceptibility profiles, in vitro presence of lipase and secre...

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Comparison of killing activity of caspofungin against Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis.

methods. In the other instance, a BLPAR strain was designated ampicillin-susceptible by Etest (MIC 1⁄4 1 mg/L), ampicillinintermediate by M.I.C.E. (MIC 1⁄4 2 mg/L) and ampicillin-resistant by BMD (MIC 1⁄4 16 mg/L). As stated earlier, the low MICs when gradient methods were used were because of a faint growth within the inhibition zone that was difficult to detect at 24 h. In contrast to the fin...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2009

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.02379-08